Tuesday, 18 December 2012

BioLargo Achieves Breakout Milestones in Advanced Wound Care on Track for FDA 510(k) Submission and Commercialization



LA MIRADA, Calif. - BioLargo, Inc. announced (12-17-2012) that had accomplished a number of significant achievements in its march toward commercialization of advanced wound care products featuring its patented BioLargo technology.

First, preliminary formulations of its antimicrobial “hydrogel” and “liquid wound cleanser” products have passed rigorous third party laboratory testing validating both efficacy and safety. Independent testing has verified both rapid and effective control against a host of dangerous pathogens commonly encountered in the wound care field. Testing of the company’s liquid formula verified efficacy against antimicrobial resistant species referred to by the CDC as the “ESKAPE” pathogens – enterococcus faecium (VRE), staphylococcus aureus (MRSA), klebsiella species, acinetobacter baumannii, pseudomonas aeruginosa, and enterobacter.

Second, it has entered into a strategic alliance with a state-of-the-art FDA registered and a current good manufacturing practices (“cGMP”) drug and device manufacturing company located in Florida, which will provide a host of services, including laboratory, regulatory, manufacturing, quality assurance, and supply chain. Formulated Solutions, LLC will help BioLargo deliver market-ready products that feature the BioLargo’s technology as soon as possible in the second half of 2013. They will finalize and test product formulations and complete the required data sets required to file the 510(k) premarket notification application with the FDA.

Third, BioLargo changed the name of its medical products subsidiary to Clyra Medical Technologies, and added former executives from global wound management companies to its leadership team. Former Smith & Nephew vice president Tanya Rhodes, and BlueSky Medical Group’s co-founder Tim Johnson, joined the management team. Steven Harrison and Robert Szolomayer of BioLargo have joined Clyra as president and vice president, respectively. Clyra will produce, market and distribute medical products featuring BioLargo’s technology. 

“Our wound care applications showcase our mission to ‘make life better’, and should prove out as a highly disruptive technical advancement in this competitive marketplace”, stated Dennis Calvert, President & CEO of BioLargo. “The industry is struggling with a host of issues that we provide a solution to: the need to avoid microbial resistance, a need for gentle but effective ingredients that are readily metabolized by the body, products that can be used across a broad spectrum of pathogens, and cost savings. We also have initiated discussions to advance our work in the area of biofilm management for chronic wounds, which we began with our technical proof of claims at the University of Hawaii years ago. As a result of our discussions with key opinion leaders from the industry and our meaningful progress, we are excited about this venture and the future impact we hope it will have in the industry and for our shareholders.”

Thursday, 22 November 2012

BioLargo's Best of Times- Thanksgiving 2012

Dear Fellow Shareholder-
        
Charles Dickens' famous words 'It was the best of times, it was the worst of times' describe the push and the pull between polar opposites of love and hatred, a persisting paradox of epoch proportion. Regardless of your belief system, your political slant, or your 'glass-half-full or glass-half-empty' world-view, one cannot deny our world has been a bit upside down.

Similarly, in the face of uncertain external forces beyond our control, which often seem as though they persist way too long, one might ask- how is it that BioLargo continues to advance? and why we are thankful? and how can our expectations of the future remain optimistic? There are a number of key reasons that BioLargo is able to enjoy its 'best of times' thus far.

Technology- Our world-class technology solves some of the most challenging problems that threaten our water, food, agriculture, healthcare and energy. We believe our breakthrough work in treating contaminated water will make our technology a game changer for multiple global industries. Scientific proof of its claim is slated for peer-reviewed publication soon.

Purpose- We are charged to 'make life better' and believe our world-class technology, as it is put to work, will help us become a world-class company of great value. Doing good and making money is a powerful motivator.

Team- We have surrounded our company with leading experts from various industries to help us focus on solving specific problems of high value. Our team is time tested and committed to our success. They joined us because they know what we can accomplish as a team.

Focus- Our path ahead for our animal care and odor control products is well defined and marching ahead. While we have not yet been able to rely on Central Garden and Pet since our product introduction at SuperZoo 2012, we have continued to advance the products and develop complimentary selling channels. We continue to receive glowing support for our cat litter additive product and believe, with the team we are assembling for marketing and sales, our success is imminent.

Our work in the advanced wound care field is precise, not complicated, and will allow us to apply for 510k clearance with the FDA in the mid to late 2013. If we can stay on schedule, we could be cleared a few months later, to take product to market and begin generating revenues from this subsidiary.

Our work with the University of Alberta, industry stakeholders, and the Canadian Government, tasked to solve the contaminated water issues associated with the oil sands tailings ponds, has verified our major technical breakthroughs which also helps set the stage for us to serve other industry segments, such as hydraulic fracking and industrial water users that can benefit from our commercial offering. We are developing commercial strategies now.

Principles and Managing Risk- The diversity of applications for our technology continues to present meaningful and diverse business opportunities as we push through various barriers to entry. Our principle business model remains licensure, but we have been forced to do more work than initially anticipated in order to succeed. We face this increased burden because most of the companies we target for licensure have been forced to consolidate operations and lower their own risk profile.

In addition to just plain hard work, there are a list of principles that help define our business; our willingness and commitment to run a lean operation with a culture of integrity, invest cautiously, seek risk-sharing partnerships from industry, continue to do as much work as we are able in spite of limited resources, maintain a willingness for management to continue to invest in our company through stock purchases, preserve and protect our shareholder equity for all of our shareholders (remember that our existing debt is convertible to equity on fixed term and price and we have only one class of stock), remain patient as we refine and narrow our business focus. These attributes continue to enable us to survive where other technology companies often fail. Of course, we could not succeed without the continued investor support we have enjoyed. We believe our breakthroughs and focus will take us from 'survive' to 'thrive' as we push ahead. We are steadfast and sure.

We are thankful for you and excited about our future!

Please take time to tell your friends about our company and as always, call me anytime I can be of assistance.

Warmest Regards,  

Dennis Calvert
President & CEO
949-643-9540
Symbol:  BLGO.OB  

Wednesday, 31 October 2012

BioLargo's Odor-No-More Adds Pet Industry Experts to Lead National Marketing Campaign for Its Cat Litter Additive Product


LA MIRADA, CA--(Marketwire - Oct 1, 2012) - BioLargo, Inc. ( OTCBB : BLGO ) announced today that it had retained Bulldog Marketing & Sales, Inc., out of New York and Bulldog's strategic Public Relations partner, K. Sutherland PR, of Irvine, CA to act as "senior strategists" as it prepares to launch a national marketing and public relations campaign to support its Odor-No-More® branded Cat Litter Additive and Central Garden & Pet's national distribution channel.
Led by John Cullen, named in the Pet Industry's Top 25 to Watch for 2011 by Pet Product News, Bulldog specializes in the marketing and sales of pet products. With over 15 years in the business, Cullen has led successful campaigns for both large and small companies. "After seeing Odor-No-More's product demo at SuperZoo 2012, I knew I had to get involved," stated Cullen. "With its instant odor removal and rapid liquid absorption, all packed into its small lightweight shaker bottle packaging, Odor-No-More is a game changer in the litter category."
"We are excited to add these key team members who have proven marketing expertise," stated BioLargo's president, Dennis Calvert. "We are leveraging the excitement generated at SuperZoo with a marketing campaign that will utilize a multi-media, multi-channel strategy to drive customer awareness."
The top two pain-points and consumer complaints about cat ownership is litter box urine smell and heavy litter bags. Odor-No-More solves both of these issues with one, simple to use product. In addition, early test market results show that once consumers try Odor-No-More they come back to purchase again and again -- making a product trial the central focus of BioLargo's marketing campaign.
About Bulldog Marketing & Sales, Inc.
Bulldog Marketing & Sales, Inc. is a full service agency formed in 2009 by pet industry veteran John Cullen. It has over 15 years of marketing and sales experience ranging from marketing strategy to new product development and retail sell-in. It has increased sales and developed new products for the Fortune 500 as well as for start-ups. Marketing & sales expertise includes: Pet Products, Consumer Packaged Goods and Consumer Electronics.
Bulldog is headquartered in the New York City. For more information, visit www.bulldogms.com.


Friday, 31 August 2012

Bagged Lettuce or Bulk? Food Safety Experts offer advice - NBC News Article Points to BioLargo and Isan System Opportunity

Bagged lettuce or bulk? Experts offer food safety advice
NBCNews.com
Benjamin Sklar / AP Prewashed, packaged salad may be more convenient for consumers, but some worry that bagged lettuce is more likely to be contaminated.

A recall this week of 8,000 cases of Fresh Express Hearts of Romaine salad marks the sixth time since April that the nation’s top producers of bagged lettuce have pulled products because of worries about food safety.

Listeria was the problem that forced Fresh Express officials to recall certain 10-ounce bags of the greens, the same potentially dangerous bug that led Dole Fresh Vegetables to withdraw bagged salads four times since spring, most recently on Aug. 22.

No illnesses have been tied to the voluntary withdrawals and company press releases describe each one as an “isolated incident” unlikely to harm human health.

But for consumers roaming the produce aisles at the grocery store, each new recall raises the question: How safe is my salad?

Food safety experts say they hear all the time from shoppers wondering which is better, bagged lettuce or the loose variety.

“We call it faith-based food safety,” says Doug Powell, a professor of food safety of Kansas State University. “And most of it is faith-based.”

Powell and Christina Bruhn, a researcher in food science and technology at UC Davis, say that while figuring out what fraction of the lettuce may make you sick is a gamble, they still place their bets on the bagged stuff.

“I do know some professionals who do not buy bagged lettuce,” says Bruhn. “I buy it. I like the convenience. I think they do the best job of anyone of cleaning the product, better than I do. They use chlorinated water. They wash it really thoroughly.”

She figures the big manufacturers, including Dole and Fresh Express, have a huge stake in safety and an incentive to get it right.

“They have the size of staff and the resources to use the most up-to-date processes,” she said.

Powell, too, says he usually opts for bagged lettuce.

“I go to the biggest grocery store I can find,” he said. “They have requirements for what they put on the shelf.”

Some consumers, haunted by the 2006 outbreak of E. coli O157 in spinach that sickened 205 people and killed three, have sworn off bagged greens.

Others, worried about contamination from fields and shipping, cringe at the thought of gritty bulk lettuce and take comfort in the “triple-washed” claims on the shiny bags. Still others swear by farmer’s market produce -- or eat only the greens they grow themselves.

About 9 billion pounds of lettuce is produced in the U.S. each year, according to the U.S. Department of Agriculture, and, to be sure, the vast proportion of it is safe.

Story: Garden Fresh recalling 7 tons of packaged salads

Indeed, Marty Ordman, a spokesman for Dole, said the company has hired two third-party listeria experts in the wake of the recent recalls, which were prompted in part by Food and Drug Administration inspections. The experts hope to help identify any potential improvements to the processes and procedures used in Dole's bagged salad plants.

Additionally, Dole scientists have been working "very closely" with the FDA to find alternative methods of sanitizing products to control contamination while still providing fresh, high quality products, Ordman added.

But Seattle food safety lawyer Bill Marler, who regularly represents clients hurt or killed by tainted produce, isn't convinced. Asked what kind of lettuce he prefers, he said: "Not bagged."

Even the crisp heads of lettuce in a farmer's market stall can be suspect, said Powell. They may be fresh and local, but that’s no guarantee of safety.

“The lettuce was sitting swamped in water for days,” he said. “If I go to a farmer’s market, I don’t want to know that it’s lovingly grown. I want to know you’ve taken steps for microbiological safety. If you can't answer those questions, I don't want to buy your lettuce."

Both Bruhn and Powell acknowledge that the big growers can have problems, as evidenced by the recent recalls. And both are big proponents of companies posting their food testing results publicly and marketing the safety of their products as a selling point.

Bruhn is also a staunch advocate of irradiation, which she says can ensure food safety.

She encourages consumers to take steps to avoid compromising bagged lettuce. Buy only bags kept very cold in the grocery store and pay attention to sell-by dates. Once you’ve got it home, open the bag and dump it directly into a clean bowl.

“Don’t stick your own hands in there,” she said.

She also urges home cooks not to re-wash bagged greens because of the possibility of cross-contamination with other bacteria already in the kitchen.

If you want to use bulk lettuce, make sure to clean it correctly, Bruhn said. First, wash your hands and also the sink with hot soapy water.

Then, break off each lettuce leaf individually, rinse it under cold running water while rubbing gently. Dry in a salad spinner or with paper towels, not with cloth towels, which may transmit bacteria.

“Keep in mind, you only get about 90 percent (of the pathogens) off,” she said. “Ninety percent sounds like a lot to a lay person, but to a microbiologist, it’s hardly anything. You can’t get it all off.”


Similar Article Shows How China Struggles with Food Safety Issue

Wednesday, 22 August 2012

BioLargo (BLGO) is a Bargain at Current Levels - Green Technology Article


Green Technology Article:


BioLargo (BLGO) is a Bargain at Current Levels

POSTED BY ON AUGUST 22, 2012 IN ENVIRONMENTAL PROTECTION

BioLargo Inc. (OTCQB: BLGO), developer of Nature’s Best Solution® – a proprietary version of iodine – formed to help solve a variety of common problems around the world, appears to be a bargain at current levels. From pet supplies like those sold at PetSmart Inc. (NASDAQ: PETM) to household brands like those sold by Clorox Company (NYSE: CLX), the company is targeting a number of different industries with products moving closer to commercialization.

Heading in the Right Direction

During the second quarter, BioLargo reported revenues that jumped 13.2% due to increases across all three of its Odor-No-More branded product lines. While the company’s overhead costs appeared to increase on the income statement, this was primarily due to non-cash expenses related to the fair value of employee stock options issued.

On its balance sheet, the company reported a cash position that more than tripled to $515,304 and total assets that grew 160% to $638,006, as of June 30, 2012. The firm’s total liabilities also fell 10.6%, as it eliminated its long-term liabilities, reduced its shareholders’ deficit, and ultimately improved long-term shareholder value.

While these financials represent a very small fraction of the company’s long-term potential, they do demonstrate management’s commitment to lean operations and movement in the right direction. Moreover, the results suggest that the firm is at a tipping point where early investors may stand to make the biggest gains by purchasing ahead of the news.

A Small Fraction of Its Potential

BioLargo’s improving financial condition may be good news for investors, but the revenues represent just a small fraction of its potential. The company’s CupriDyne® technology is applicable in numerous end markets, including animal health, environmental remediation, oil and gas, consumer products, food processing, medical and water treatment.

CurpiDyne® technology is unique because it enables molecular iodine to be delivered in a calibrated dose that’s safe at high levels and efficacious at low levels. Since it’s created by combining a mineral and salt, it can be developed in numerous forms, including tablets, drops, powders and even as a water-soluble ink, depending on its targeted industry.

These target industries represent billions in potential revenue opportunity. Capturing just a small fraction of one end market would make the company’s $18 million market capitalization seem extremely cheap, much less bringing products to market in multiple industries. And recently, that’s exactly what the company has been aiming to do.

BioLargo’s Low-Hanging Fruit

BioLargo’s low hanging fruit is the animal health market, where its technology can help eliminate odor. In March of 2011, the company signed an exclusive license and supply agreement with Central Garden & Pet Company (NASDAQ: CENT) – a nearly $2 billion company that’s a leader in the pet and lawn care industries.

From the outside looking in; the pet industry has 2 major pet shows where products are typically launched, Global Pet (which is hosted in the late spring) and the upcoming Super Zoo 2012, which will be held in September. If Central wants to hang on to its exclusive rights then one might assume that they would likely want to get started with product introductions this fall. The agreement calls for the purchase of at least 1.25 million pounds of product by March 2013, and in the two years after that, the agreement calls for the purchase of at least 2 million and 2.75 million pounds of product, respectively for Central to maintain its exclusive rights.

Using sales figures from competing products and standard industry margins, the minimum run rate from this agreement could take the company to $3.5 million to $5 million per year. These figures should help the firm expand its revenues and generate positive cash flow over time, while building in value with a guaranteed 3% increase in the agreement each year its extended.

BioLargo Moves into Wound Care

BioLargo may already be undervalued given its pet products, but there’s even more value in the other industries it’s targeting. In May of 2012, the company announced that it formed a subsidiary – BioLargo Medical Group Inc. – to advance proof of claims and pursue regulatory approvals in the $19 billion advanced wound care industry.

The wound care industry faces many problems, including the threat of microbial resistance. With many wound care products employing antibiotics, the increasing exposure to humans has produced resistance bacteria like c.diff and staph. BioLargo’s product does not use antibiotics and therefore may find itself in high demand within the industry.

In August, the company added former Smith & Nephew Wound Management Vice President Tanya Rhodes to its management team as a senior strategy advisor. With more than 20 years of experience in the industry, bringing staple wound care technologies to market, Ms. Rhodes is the perfect person to help the company expedite this new lucrative line of business.

Starting to Look into Oil & Gas

BioLargo is also actively pursuing development in the oil and gas industry. In particular, the company’s antibacterial products provide oil and gas companies with a way to solve many of their environmental problems. The company’s technology can be used to do everything from treating flowback water in fracking to cleaning up the water used in oil sands projects in Canada.

Last December, the company was selected as a Founding Member of a Canadian Government backed research chair to develop sustainable solutions for the oil sands industry. Water released from the oil sands is expected to reach one billion cubic meters in the Athabasca oil sands region alone by 2025, creating significant demand for a solution.

Consumer, Dairy & Much More

BioLargo’s opportunities extend even beyond these industries. In a March 2012 press release, the company elaborated on several other projects it’s working on:

  • BioLargo developed a free iodine liquid wash and hydrogel product for both consumers and companies. The company has already made initial sales to consumers and has begun to deliver the products to industrial customers for trials.
  • BioLargo contracted a dairy industry distributor called Green Alpha Solutions LLC that will utilize its products to prevent infections and enhance the quality and quantity of dairy products produced in the $35 billion industry.
  • BioLargo developed a family of consumer products called DeodorAll™ that remove household stains and odors. The Home Shopping Group will produce, manage and broadcast a series of direct response campaigns over the coming months.

Enormous Opportunity at a Small Cost

BioLargo represents an enormous opportunity for shareholders given its ongoing progress in these many end markets. With a market capitalization of under $18 million, investors can purchase the stock for a fraction of its potential valuation. Meanwhile, the company’s improving financials and recent sales suggest that it will become cash flow positive over the near term.

The company’s platform technology and broad potential across many markets provides investors with greater diversification and lower risk. Meanwhile, the firm’s licensing business model provides investors with greater leverage, which could mean less capital outlay and higher free cash flow over time, as the company builds its pipeline of products.

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Monday, 20 August 2012

E.coli fears prompt another lettuce recall- Points to BioLargo's Opportunity for Isan System


August 20, 2012 3:53 AM

E.coli fears prompt romaine lettuce recall(CBS/AP) SALINAS, Calif. — A Northern California produce supplier said Sunday it is voluntarily recalling romaine lettuce that was shipped to 19 states, Puerto Rico and Canada over fears about possible E. coli contamination.

Salinas-based Tanimura & Antle said the recall is limited to a single lot of its Field Fresh Wrapped Single Head Romaine that was available at retail stores starting Aug. 2. The lettuce is packed in a plastic bag with the UPC number 0-27918-20314-9, and it may have a "best by" date of Aug. 19.

The lettuce is sold in nine-ounce, 9.25-, 10-, 10.25- and 16-ounce bags under the labels Ready Pac, Trader Joe's, Safeway and Dining in Classic, says CBS station KPIX in San Francisco.

The company said some 2,095 cases were potentially affected. Of those, 1,969 cases were shipped to Puerto Rico and the following states: Alabama, Arkansas, Arizona, California, Georgia, Kansas, Kentucky, Maryland, North Carolina, New Mexico, Nevada, New York, New Jersey, Pennsylvania, South Carolina, Tennessee, Texas, Virginia and Washington.

The product was packed with either 12 or 18 heads per case.

The recall was being conducted in consultation with Food and Drug Administration, and was based on the testing of a random sample by the Canadian Food Inspection Agency. There have been no reported illnesses associated with consumption of this product.

© 2012 CBS Interactive Inc. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed. The Associated Press contributed to this report.

Thursday, 9 August 2012

Capitalize on the Recession-Resistant Pet Industry

BioLargo (BLGO): Capitalize on the Recession-Resistant Pet Industry

POSTED BY ON AUGUST 8, 2012 IN ENVIRONMENTAL PROTECTION
Biolargo OdorNoMore Litterbox

BioLargo Inc. (OTCBB: BLGO), developer of Nature’s Best Solution® – a proprietary version of iodine – formed to help solve a variety of common problems around the world, has been largely focused on the pet industry through its agreement with Central Garden & Pet Co. (NASDAQ: CENT) to develop its product that could eventually hit retailers like PetSmart Inc. (NASDAQ: PETM) and Petco, (a privately held company).

Large & Growing Industry

The pet industry is a large and growing industry in the United States. Currently, more than 62% of U.S. households own a pet, while spending on pets has increased from $17 billion in 1994 to nearly $53 billion in 2012. Moreover, growth in spending has been consistent during economic downturns throughout that period, making it a relatively recession-resistant industry.

When you start to add up the annual average associated costs from owing a cat for instance; such as vet visits ($655), food & treats ($324), boarding ($274), vitamins ($95), grooming ($73), and toys ($43) the annual amount of money spent can become staggering. It is obvious from watching the trend of animal ownership (92 million cats & 78.2 million dogs in 2011), as well as annual U.S. pet industry expenditures, that Americans love their pets, and are more than willing to spend money on them.

The pampering of pets has shown a phenomenal growth curve in the last two decades. From the creation of doggy day care to the purchase of all kinds of high-end accessories, products for our companion animals now extend well beyond the traditional ‘necessities’ of the past. Big name companies such as Paul Mitchell, Omaha Steaks, Harley Davidson (NYSE: HOG), and Old Navy have all reacted to this uptick in spending by introducing lines of pet products ranging from dog shampoo to pet attire.

Of the $53 billion pet market; some $11.77 billion of that is spent on pet supplies and over the counter medicine, including cat litter boxes and bedding for horses. BioLargo hopes to capitalize on these markets with its unique Odor-No-More products; designed to create a cleaner and drier litter box without the odor for cats, and for use as an effective bedding alternative for horses. The inventor of “kitty litter” (Ed Lowe) once stated, “This is a recession- proof business, people will go without a lot of things before they’ll go without their cats. And they’re not going to have cats without litter.”

Cats and other true carnivores metabolize a higher percentage of protein than omnivores, which leads to particularly nasty smelling feces. As a result, the industry has developed what it terms second and third-generation litters. Second generation litters originally involved adding highly proprietary perfuming agents to the litter, which simply tried to mask the scent. But as the market grew, and research and development teams scrambled to find agents that would prevent the odor from forming, a third generation of litters came into existence that aimed to slow microbial growth by treating the litter with a mild disinfectant. Stronger disinfectants would seem a simple answer to the odor problem for the entire industry, but all companies walk the fine line between what’s bad for bugs but okay for cats and people, and that is where BioLargo’s proprietary version of iodine comes into play.

Industry-Leading Partnership

Last year, BioLargo announced an agreement with Central Garden & Pet Supply Co., a leading marketer and producer of premium pet supplies in the United States. Under the agreement, the two companies will develop, produce and sell products that they believe will be most successful in the pet supplies industry, including BioLargo’s Odor-No-More product lineup.

“Most of [Central’s] brands are the number one or two brand in their respective U.S. market categories,” stated Dennis Calvert, CEO of BioLargo Inc. “They operate the largest sales and logistics network in the industry, which strategically supports its [and our] brands. With sales of more than $840 million annually, we believe they are the perfect partner for BioLargo.”

Fragmented with Need for Innovation

Despite the pet industry’s large size, the market remains very fragmented with over 500 manufacturers in the U.S. alone. Many of these smaller companies have limited production capabilities, and as a result a small number of industry players such as Mars Corporation, Hartz Mountain Corporation and Central Garden & Pet Co., end up controlling most of the industry’s volume.

Meanwhile, the lack of major competitors has starved the industry of innovation. Many pet products are based on concepts that were invented decades ago, with the exception of food choices, leaving many of man’s best friends to wonder why the neglect? BioLargo hopes that its products will help drive innovation in the industry, particularly when it comes to pet odor elimination and sanitization.

Great Investment Opportunity

BioLargo represents a great investment opportunity with a market capitalization of just over $18 million. Capturing just a fraction of the $11.77 billion U.S. pet supplies market could equate to hundreds of millions of dollars in revenues. And with its agreement with Central Garden & Pet, the company is uniquely positioned to do so over the near-term.


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